Internal Reference:
0695-HE003005-200-1G
Website URL:
/shop/0695-he003005-200-1g-sh-peg-nh2-hcl-mw-200-1-gram-36122
Purity: ≥95%
Recommended Storage Conditions: Store at -5°C,keep in dry and avoid sunlight.
Uses：
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Background:
Thiol PEG Amine (SH-PEG-NH2.HCI) is a linear heterobifunctional PEGylation reagent with a thiol and an amine moiety. It can be used to modify proteins, peptides, and other materials or small molecules. The amino group (-NH2) can easily form stable amide bonds with carboxyl groups, as well as with reactive esters (-NHS) at pH 7-8.5. Thiol groups (-SH) and maleimide can easily form stable thioether bonds at PH6.5-7.5. Thiol (-SH) groups have high affinity for gold surfaces and are widely used for gold nanoparticles or gold film modification. PEGylation improves solubility and stability and reduces the immunogenicity of proteins and peptides. It can also inhibit the non-specific binding of charged molecules on the modified surface.
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