Cyclosporin A Mouse Monoclonal Antibody [Clone ID: 4A3 (CSZ.22)] - 200 ug

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Internal Reference: 0937-BM941
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Clone Name	4A3 (CSZ.22)
Applications	ELISA
Recommended Dilution	ELISA.
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	Cyclosporin A conjugated to an HMW carrier
Specificity	This antibody recognizes Cyclosporin A, a widely-used immunosuppressant drug from the fungus Tolypocladium inflatum.
Formulation	PBS State: Purified State: Liquid (0.45 µm filtered) purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Background	Cyclosporin is used to prevent rejection following solid organ and bone marrow transplantation . It has been estimated that cyclosporine is given to more than 90% of children who have received a kidney transplant in the United States. In addition, the ability of cyclosporin to inhibit T-cell activation has been shown to have a role in the treatment of diseases such as nephrotic syndrome, refractory Crohn's disease and ulcerative colitis, biliary cirrhosis, aplastic anemia, rheumatoid arthritis, myasthenia gravis, and dermatomyositis.