Purity: Greater than 95% as determined by SDS-PAGE.
Endotoxin: Less than 1.0 EU/ug as determined by LAL method.
Activity: ①Measured by its binding ability in a functional ELISA. Immobilized human SEMA4D at 2 μg/mL can bind biotinylated Pepinemab, the EC50 is 1.005-1.776 ng/mL. ②Measured by its binding ability in a functional ELISA. Immobilized human SEMA4D at 5 μg/mL can bind human PLXNB1 (CSB-MP018222HU2k6), the EC50 is 0.8179-1.357 μg/mL.
Target Names: SEMA4D
Uniprot No.: Q92854
Alternative Names:
(A8)(BB18)(GR3)(CD100)