Assay type: Sandwich
Sensitivity: 32.95ng/L
Detection range: 70-15000ng/L
Sample type: Serum, plasma, cell culture supernates
Species: Human
Storage: 2-8ºC
Assay time: 1h 30m
MASS (Da): 39,838
GeneID: 9478
Synonyms: CABP 1; CABP1; Calbrain; Calcium-binding protein 1; Caldendrin
Target protein: CABP1
Background:
Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs)(PubMed: 14570872). Inhibits agonist-induced intracellular calcium signaling (PubMed: 15980432). Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium Channels (PubMed: 11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium Channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on Channel function (PubMed: 15140941). Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 Channels (PubMed: 15895247). Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity).