Ketanserin (Vulketan Gel) - 50 mg

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    Expédition : 2-3 jours ouvrables


    Référence interne: E1KS2232
    URL du site web: /shop/e1ks2232-ketanserin-vulketan-gel-50-mg-7094

    Ketanserin is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A. Ketanserin is a drug with affinity for multiple G protein-coupled receptors. Ketanserin inhibits rat and human 5-HT2C with Ki of 50 and100 nM, respectively and has higher affinity binding for alpha-1 adrenergic (Ki = ~ 40 nM) and Histamine H1 (Ki = 2 nM). Ketanserin can also be used to discriminate between 5-HT1D and 5-HT1B receptor subtypes. Ketanserin has antihypertensive properties. Ketanserin also reduces platelet aggregation produced by serotonin. Ketanserin also has high affinity for alpha-1 adrenergic receptors, and very high affinity for histamine H1 receptors. Ketanserin was shown to reduce the severity and frequency of the vasospasm in Raynaud’s phenomenon.

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